Dr. Young is a clinical biochemist whose major research interests are in the biochemistry and physiology of heparin, an anticoagulant used extensively in the prevention and treatment of thrombosis and pulmonary embolism. His research has helped to explain the effect of heparin-binding proteins in plasma and their role in the variability of the anticoagulant response to heparin and to the phenomenon of heparin resistance. A new class of anticoagulants called low molecular weight heparins have been developed as an alternative to heparin. Despite their increasing clinical use, the mechanisms responsible for the superior pharmacokinetics of low molecular heparin over heparin are is still poorly understood. His current research projects involve studying the role of the liver and kidneys in the clearance and metabolism of heparin and low molecular weight heparins. He is also investigating the anti-inflammatory effects of low molecular weight heparins and heparinoids lacking anticoagulant activity. His other interests include the effect of heparin on bone and the anticoagulant and antithrombotic effects of novel heparin-like compounds. Dr. Young is the Discipline Director of Clinical Chemistry and Immunology within the Hamilton Regional Laboratory Medicine Program and is based in the Core Laboratory, Henderson General Hospital.